The science
Innovative Technology
Aegros HaemaFrac® significantly reduces production steps compared to current technology
Plasma preparation
Protein capture
Ultrafiltration/ diafiltration/ concentration
Viral filtration
Final product
Aegros’ process connects to the front and back end of the Cohn process replacing the multiple capture steps with a single capture step. This increases overall process yield, reduces process time, steps and cost making plasma fractionation viable at the 50,000L level.
Aegros HaemaFrac® leverages the principles of electrophoresis—specifically ion mobility in an electric field—combined with pH modulation and membrane-based separation to efficiently isolate plasma proteins at therapeutic scale. By using buffers to regulate the charge on proteins and employing selective migration techniques, Aegros has created a platform for high-yield, high-purity plasma protein isolation. This innovation marks a significant advancement over traditional electrophoresis methods, making it a powerful tool for the production of plasma-derived therapies. The ability to scale this technique for industrial applications holds the potential to revolutionize the production of critical therapeutic proteins with enhanced guarantees of purity and performance.
